
High on Life has different Alien Bosses that players will get to defeat before they get to the final Boss fight to free the Human Kind. One of the end-game main bosses that Gene Zaroothian will ask you to kill is Nipulon.
In this guide, we’ll tell you how to defeat Nipulon in High on Life.
Location of Nipulon
Nipulon is a G3 Chief of Customer Liaisons who can be found in Port Terrene. You can get there by going to the Old Town through the teleport and following through the waypoint. You will get this bounty, once you have defeated four G3 Cartel Bosses. After that, you will get to save Lizzie and then Gene Zaroothain will ask you to kill the second-in-command boss named “Nipulon”. You will have to interact with the Bounty 5000 machine to accept the bounty of Nipulon and then the portal will open the side of the machine which will take you to the Old Town.
You will reach Port Terrene where you will have to take down the G3 Cartel security and then ascend to Nipulon’s Lounge to encounter him in a boss fight.
Defeating Nipulon
You will start the fight with Nipulon in his lounge and he will be using a semi-auto pistol. At the start just shoot him with different guns and you can also get close to him and deal high damage to him with Gus. Use the Shotgun Fire to deal more damage and you can also use Sweezy’s Time Bubble to slow him down. Once you have depleted a quarter of his HP, he will activate the shield that covers him from the bullet. You will not be able to deal any damage to him while his shield is on. He will also release a drug gas in the room that will make you feel high and you will get to another place.

You will be in a loop of a location in Blim City and you will not get out of here until you talk with Gene Zaroothian. After talking to Gene, a black hole will appear on the side and you have to jump in the hole. After a moment, you will start seeing many fake Nipulon as you fall down. Keep shooting the Nipulon until the real Nipulon joins in. The real Nipulon will be of Yellowish Color and the fake ones will be Greenish. So, look around to find the real Nipulon and start shooting him. He will scramble often with the fake ones so you will have to find him a few times to deal damage.
Once you have depleted more of his HP, you will get to another place where you will find Lizzie. Talk to Lizzie and after that, another Black Hole will appear. Jump into the Black Hole and you will get to fight Nipulon again. He will summon fake Nipulons again they will be shooting lasers and rotating in a circle. However, the real Nipulon will not be shooting and he can easily be identified with fake Nipulons. Look for Yellowish Color Nipulon who is not shooting the laser and then just start shooting him to deal damage.

After depleting more of his HP, you will get to another place where you will have to collect all four of your talking guns from different platforms. They all will be close to each other and after picking them up, another Black Hole will appear. Jump into the black hole and you will be in another hallucination and you will get back to Nipulon Lounge. You will be using all four of your guns at the same time and taking down all of the Fake Nipulons in front to reach the real Nipulon. Once you have reached the real Nipulon, interact with him to use Knifey to Stab him multiple times and kill him.
After that, you will be able to get his DNA and return home to turn in his bounty to complete the bounty.
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